Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002586)
Formula
CYP3A4 ...
SVG example
Reactant 3-hydroxycarbamazepine Product 2,3-Dihydroxycarbamazepine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002589 Carbamazepine 3-hydroxycarbamazepine Oxidation - 3-Hydroxylation Carbamazepine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002583 2-hydroxyiminostilbene Iminoquinone Unclear Carbamazepine [1]
References
1 Carbamazepine and its metabolites in human perfused placenta and in maternal and cord blood Epilepsia. 1995 Mar;36(3):241-8. doi: 10.1111/j.1528-1157.1995.tb00991.x.

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