Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002589)
Formula
CYP3A4 ...
SVG example
3-Hydroxylation
Reactant Carbamazepine Product 3-hydroxycarbamazepine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Metabolic Type Oxidation - 3-Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002588 Carbamazepine 10,11-Epoxycarbamazepine Oxidation - 10,11-Epoxidation Carbamazepine [1]
MR002587 Carbamazepine Carbamazepine 2,3-epoxide Unclear Carbamazepine [1]
MR002590 Carbamazepine Carbamazepine N-glucuronide Conjugation - N-Glucuronidation Carbamazepine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002586 3-hydroxycarbamazepine 2,3-Dihydroxycarbamazepine Unclear Carbamazepine [1]
References
1 Carbamazepine and its metabolites in human perfused placenta and in maternal and cord blood Epilepsia. 1995 Mar;36(3):241-8. doi: 10.1111/j.1528-1157.1995.tb00991.x.

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