Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002799)
Formula
SVG example
Reactant Adinazolam Product Alpha-hydroxyalprazolam
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002798 Adinazolam Desmethyladinazolam Oxidation - N-Demethylation Adinazolam [1]
MR002801 Adinazolam Estazolam Unclear Adinazolam [1]
MR002800 Adinazolam N-demithyladinazolam Unclear Adinazolam [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009848 Alprazolam Alpha-hydroxyalprazolam Unclear - Unclear Alprazolam [2]
References
1 Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man. J Pharm Pharmacol. 1998 Mar;50(3):265-74.
2 Drug metabolism in human brain: high levels of cytochrome P4503A43 in brain and metabolism of anti-anxiety drug alprazolam to its active metabolite

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