Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002806)
Formula
SVG example
Reactant Amodiaquine Product Amodiaquine metabolite CARBOXYLIC ACID
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002804 Amodiaquine Amodiaquine metabolite AQCYS Unclear Amodiaquine [1]
MR002803 Amodiaquine Amodiaquine metabolite AQGT Unclear Amodiaquine [1]
MR002805 Amodiaquine Amodiaquine metabolite BISDEAQ Unclear Amodiaquine [1]
MR002802 Amodiaquine Desethylamodiaquine Oxidation - N-Deethylation Amodiaquine [2]
References
1 Role of hepatic metabolism in the bioactivation and detoxication of amodiaquine Xenobiotica. 1995 Feb;25(2):199-217. doi: 10.3109/00498259509061845.
2 Cardiovascular concentration-effect relationships of amodiaquine and its metabolite desethylamodiaquine: Clinical and preclinical studies. Br J Clin Pharmacol. 2023 Mar;89(3):1176-1186. doi: 10.1111/bcp.15569.

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