Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002802)
Formula
SVG example
N-Deethylation
Reactant Amodiaquine Product Desethylamodiaquine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C8 (CYP2C8) DME Info
Metabolic Type Oxidation - N-Deethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002804 Amodiaquine Amodiaquine metabolite AQCYS Unclear Amodiaquine [1]
MR002803 Amodiaquine Amodiaquine metabolite AQGT Unclear Amodiaquine [1]
MR002805 Amodiaquine Amodiaquine metabolite BISDEAQ Unclear Amodiaquine [1]
MR002806 Amodiaquine Amodiaquine metabolite CARBOXYLIC ACID Unclear Amodiaquine [1]
References
1 Role of hepatic metabolism in the bioactivation and detoxication of amodiaquine Xenobiotica. 1995 Feb;25(2):199-217. doi: 10.3109/00498259509061845.

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