Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR002838)
Formula	UGT1A9 Glucuronidation
	Reactant	Dapagliflozin		Product	Dapagliflozin 3-O-glucuronide metabolite
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	UDP-glucuronosyltransferase 1A9 (UGT1A9)					DME Info
Metabolic Type	Conjugation - Glucuronidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002839	Dapagliflozin	Dapagliflozin BMS-511926	Oxidation - O-Deethylation	Dapagliflozin	[1]
MR002840	Dapagliflozin	Dapagliflozin BMS-639432	Oxidation - Hydroxylation	Dapagliflozin	[1]

References
1	In vitro characterization and pharmacokinetics of dapagliflozin (BMS-512148), a potent sodium-glucose cotransporter type II inhibitor, in animals and humans Drug Metab Dispos. 2010 Mar;38(3):405-14. doi: 10.1124/dmd.109.029165.

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