Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002885)
Formula
CYP3A4 ...
SVG example
Hydroxylation
Reactant Saquinavir mesylate Product M2 di-hydroxylated metabolite
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 3A7 (CYP3A7) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002887 Saquinavir mesylate (2S)-N-[(2S,3R)-4-[(3S,4aR,8aS)-3-(tert-butylcarbamoyl)-6-hydroxy-decahydroisoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-[(quinolin-2-yl)formamido]butanediamide Oxidation - Hydroxylation Saquinavir mesylate [1]
MR002888 Saquinavir mesylate (2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-7-hydroxy-decahydroisoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-[(quinolin-2-yl)formamido]butanediamide Oxidation - Hydroxylation Saquinavir mesylate [1]
MR002886 Saquinavir mesylate (2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-[(1-hydroxy-2-methylpropan-2-yl)carbamoyl]-decahydroisoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-[(quinolin-2-yl)formamido]butanediamide Oxidation - Hydroxylation Saquinavir mesylate [1]
References
1 DrugBank(Pharmacology-Metabolism)Saquinavir mesylate

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