Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002908)
Formula
SVG example
Oxidation
Reactant Triclabendazole Product TCBZ-SX
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002910 Triclabendazole keto-triclabendazole Unclear Triclabendazole [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002909 TCBZ-SX Triclabendazole sulfone metabolite Oxidation - Oxidation Triclabendazole [1], [2]
References
1 Total determination of triclabendazole and its metabolites in bovine tissues using liquid chromatography-tandem mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Mar 1;1109:54-59. doi: 10.1016/j.jchromb.2019.01.021.
2 Egaten FDA label

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.