General Information of This Metabolic Reaction (MR) (ID: MR002950)
Formula
DCK ...
SVG example
Phosphorylation
Reactant Nelarabine Product Ara-G
Reactant Info Product Info
Metabolic Enzyme Deoxycytidine kinase (DCK) DME Info
Deoxyguanosine kinase (dgk) DME Info
Metabolic Type Other reaction - Phosphorylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002951 Nelarabine Arabinofuranosylguanine Oxidation - Demethylation Nelarabine [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002949 Ara-G Ara-GTP Unclear Nelarabine [3]
References
1 DrugBank(Pharmacology-Metabolism)Nelarabine
2 FDA Approved Drug Products: ARRANON? (nelarabine) Injection FOR INTRAVENOUS USE
3 U. S. FDA Label -Nelarabine

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