Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003099)
Formula
SVG example
Glucuronidation
Reactant Fenofibric acid Product Fenofibryl glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003100 Fenofibric acid Fenofibrate metabolite X Conjugation - Methylation Fenofibric acid [1]
MR003098 Fenofibric acid Reduced Fenofibric Acid Reduction - Reduction Fenofibric acid [2]
MR003096 Fenofibric acid Fenofibrate metabolite X Conjugation - Methylation Fenofibrate [1]
MR003094 Fenofibric acid Reduced Fenofibric Acid Reduction - Reduction Fenofibrate [2]
References
1 Fenofibrate: metabolism and species differences for peroxisome proliferation in cultured hepatocytes Fundam Appl Toxicol. 1995 Jun;26(1):63-74. doi: 10.1006/faat.1995.1075.
2 In vitro metabolism of fenofibric acid by carbonyl reducing enzymes. Chem Biol Interact. 2016 Oct 25;258:153-8.

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