Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003113)
Formula
SVG example
Demethylation
Reactant Levomethadyl acetate hydrochloride Product NorLAAM
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003114 Levomethadyl acetate hydrochloride . Unclear Levomethadyl acetate hydrochloride [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008030 Levomethadyl Acetate Noracymethadol Oxidation - N-demethylation Levomethadyl Acetate [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003112 NorLAAM Dinor-levomethadyl acetate Oxidation - Demethylation Levomethadyl acetate hydrochloride [3]
References
1 Drug Interactions Flockhart Table:Docetaxel
2 DrugBank(Pharmacology-Metabolism):Levomethadyl Acetate
3 N-demethylation of levo-alpha-acetylmethadol by human placental aromatase. Biochem Pharmacol. 2004 Mar 1;67(5):885-92.

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