Details of the Metabolic Reaction (MR)
| General Information of This Metabolic Reaction (MR) (ID: MR003127) | ||||||
|---|---|---|---|---|---|---|
| Formula | ||||||
| Reactant | Cariprazine hydrochloride | Product | Didesmethyl cariprazine | |||
| Reactant Info | Product Info | |||||
| Metabolic Enzyme | Cytochrome P450 3A4 (CYP3A4) | DME Info | ||||
| Cytochrome P450 2D6 (CYP2D6) | DME Info | |||||
| Metabolic Type | Oxidation - Demethylation | |||||
| Other MR(s) Related to The Reactant of This MR | |||||||||||||||||||||||||||||
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| Other MR(s) That Metabolize The Reactant of This MR | |||||||||||||||||||||||||||||
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| Other MR(s) Related to The Product of This MR | |||||||||||||||||||||||||||||
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| Other MR(s) That Produce The Product of This MR | |||||||||||||||||||||||||||||
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| References | ||||||
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| 1 | Cariprazine: chemistry, pharmacodynamics, pharmacokinetics, and metabolism, clinical efficacy, safety, and tolerability. Expert Opin Drug Metab Toxicol. 2013 Feb;9(2):193-206. | |||||
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