Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003159)
Formula Reactant N-hydroxyphentermine Product Nitrophentermine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003160 Phentermine N-hydroxyphentermine Oxidation - N-Hydroxylation Phentermine [1]
References
1 Determination of phentermine, N-hydroxyphentermine and mephentermine in urine using dilute and shoot liquid chromatography-tandem mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Sep 1;1029-1030:22-27. doi: 10.1016/j.jchromb.2016.06.045.

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