Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003160)
Formula
SVG example
N-Hydroxylation
Reactant Phentermine Product N-hydroxyphentermine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - N-Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003161 Phentermine p-hydroxyphentermine Oxidation - Hydroxylation Phentermine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003159 N-hydroxyphentermine Nitrophentermine Oxidation - Oxidation Phentermine [1]
References
1 Determination of phentermine, N-hydroxyphentermine and mephentermine in urine using dilute and shoot liquid chromatography-tandem mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Sep 1;1029-1030:22-27. doi: 10.1016/j.jchromb.2016.06.045.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.