Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR003207)
Formula	ES Hydrolysis
	Reactant	Ciclesonide		Product	Desisobutyrylciclesonide
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Esterases (ES)					DME Info
Metabolic Type	Hydrolysis - Hydrolysis

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR003204	Desisobutyrylciclesonide	C21-Lipid conjugation	Other reaction - Esterification	Ciclesonide	[1]
MR003206	Desisobutyrylciclesonide	Ciclesonide metabolite M2	Unclear	Ciclesonide	[1]
MR003205	Desisobutyrylciclesonide	Ciclesonide metabolite M3	Unclear	Ciclesonide	[1]

References
1	In Vitro metabolism of ciclesonide in human lung and liver precision-cut tissue slices Biopharm Drug Dispos. 2006 May;27(4):197-207. doi: 10.1002/bdd.500.

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