Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004281)
Formula
SVG example
Reactant Misonidazole Product [1-(2-aminoimidazol-1-yl)-3-methoxypropan-2-ol] (AIM)
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004284 Misonidazole Desmethylmisonidazole Unclear Misonidazole [1]
MR004278 Misonidazole Nitroso Reduction - Reduction Misonidazole [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004283 [1-(2-aminoimidazol-1-yl)-3-methoxypropan-2-ol] (AIM) (2-hydroxy-3-methoxypropyl)-guanidine (G) Hydrolysis - Hydrolyzation Misonidazole [3]
MR004282 [1-(2-aminoimidazol-1-yl)-3-methoxypropan-2-ol] (AIM) Urea Hydrolysis - Hydrolyzation Misonidazole [3]
References
1 Kinetic aspects of misonidazole and its major metabolite in radiotherapy
2 Misonidazole and other hypoxia markers: metabolism and applications
3 Comparative misonidazole metabolism in anaerobic bacteria and hypoxic Chinese hamster lung fibroblast (V-79-473) cells

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