Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004282)
Formula
SVG example
Hydrolyzation
Reactant [1-(2-aminoimidazol-1-yl)-3-methoxypropan-2-ol] (AIM) Product Urea
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolyzation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004281 Misonidazole [1-(2-aminoimidazol-1-yl)-3-methoxypropan-2-ol] (AIM) Unclear Misonidazole [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004283 [1-(2-aminoimidazol-1-yl)-3-methoxypropan-2-ol] (AIM) (2-hydroxy-3-methoxypropyl)-guanidine (G) Hydrolysis - Hydrolyzation Misonidazole [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003078 Agmatine Urea Unclear Agmatine [2]
MR000203 Ammonia Urea Unclear Ammonia [3]
MR003075 Gamma-guanidinobutyrate Urea Unclear Agmatine [2], [4]
MR004034 Allantoic acid Urea Unclear Xanthine [5]
MR005276 FUPA Urea Hydrolysis - Hydrolysis Tegafur-uracil [6]
References
1 Comparative misonidazole metabolism in anaerobic bacteria and hypoxic Chinese hamster lung fibroblast (V-79-473) cells
2 Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine Amino Acids. 2004 Feb;26(1):3-8. doi: 10.1007/s00726-003-0030-z.
3 Ammonia Transporters and Their Role in Acid-Base Balance Physiol Rev. 2017 Apr;97(2):465-494. doi: 10.1152/physrev.00011.2016.
4 A guanidine-degrading enzyme controls genomic stability of ethylene-producing cyanobacteria. Nat Commun. 2021 Aug 26;12(1):5150. doi: 10.1038/s41467-021-25369-x.
5 Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism
6 DrugBank(Pharmacology-Metabolism):Tegafur-uracil

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