Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004472)
Formula
SVG example
Reactant UDP-galactose Product Galactose-1-phosphate
Reactant Info Product Info
Metabolic Enzyme Nucleotide pyrophosphatase (Enpp1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012934 UDP-galactose Galactose Oxidation - Hydrolyzationn UDP-galactose [1]
MR012930 UDP-galactose UDP-glc Unclear UDP-galactose [2]
MR004474 UDP-galactose UDP-glc Unclear UDP-glucose [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000159 Alpha-D-galactose Alpha-D-galactose 1-phosphate Other reaction - Phosphorylation; Galactokinase Alpha-D-galactose [4], [5], [6]
MR007412 CERC-801 Galactose-1-phosphate Unclear CERC-801 [7]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012929 Galactose-1-phosphate UDP-galactose Unclear UDP-galactose [2]
MR004473 Galactose-1-phosphate UDP-galactose Unclear UDP-glucose [3]
References
1 Using a Personal Glucose Meter and Alkaline Phosphatase for Point-of-Care Quantification of Galactose-1-Phosphate Uridyltransferase in Clinical Galactosemia Diagnosis
2 UDP-galactose 4'-epimerase activities toward UDP-Gal and UDP-GalNAc play different roles in the development of Drosophila melanogaster
3 Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium
4 Molecular structure of galactokinase J Biol Chem. 2003 Aug 29;278(35):33305-11. doi: 10.1074/jbc.M304789200.
5 Enzymatic production of alpha-D-galactose 1-phosphate by lactose phosphorolysis Biotechnol Lett. 2009 Dec;31(12):1873-7. doi: 10.1007/s10529-009-0087-1.
6 The Antifungal Effects of Citral on Magnaporthe oryzae Occur via Modulation of Chitin Content as Revealed by RNA-Seq Analysis. J Fungi (Basel). 2021 Nov 29;7(12):1023. doi: 10.3390/jof7121023.
7 Molecular and biochemical characterization of human galactokinase and its small molecule inhibitors. Chem Biol Interact. 2010 Dec 5;188(3):376-85.

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