Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007412)
Formula
SVG example
Reactant CERC-801 Product Galactose-1-phosphate
Reactant Info Product Info
Metabolic Enzyme Galactose kinase (GALK1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007410 CERC-801 Galactitol Unclear CERC-801 [1]
MR007411 CERC-801 Unclear Unclear CERC-801 [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000159 Alpha-D-galactose Alpha-D-galactose 1-phosphate Other reaction - Phosphorylation; Galactokinase Alpha-D-galactose [3], [4], [5]
MR012928 UDP-galactose Galactose-1-phosphate Oxidation - Hydrolyzationn UDP-galactose [6]
MR004472 UDP-galactose Galactose-1-phosphate Unclear UDP-glucose [6]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012929 Galactose-1-phosphate UDP-galactose Unclear UDP-galactose [7]
MR004473 Galactose-1-phosphate UDP-galactose Unclear UDP-glucose [8]
References
1 Metabolism of D-galactose is dispensable for the induction of the beta-galactosidase (bgaD) and lactose permease (lacpA) genes in Aspergillus nidulans
2 Biochemical properties of L-arabinose isomerase from Clostridium hylemonae to produce D-tagatose as a functional sweetener. PLoS One. 2018 Apr 23;13(4):e0196099.
3 Molecular structure of galactokinase J Biol Chem. 2003 Aug 29;278(35):33305-11. doi: 10.1074/jbc.M304789200.
4 Enzymatic production of alpha-D-galactose 1-phosphate by lactose phosphorolysis Biotechnol Lett. 2009 Dec;31(12):1873-7. doi: 10.1007/s10529-009-0087-1.
5 The Antifungal Effects of Citral on Magnaporthe oryzae Occur via Modulation of Chitin Content as Revealed by RNA-Seq Analysis. J Fungi (Basel). 2021 Nov 29;7(12):1023. doi: 10.3390/jof7121023.
6 UDP-galactose hydrolysis in brain and its effect on cerebroside synthesis
7 UDP-galactose 4'-epimerase activities toward UDP-Gal and UDP-GalNAc play different roles in the development of Drosophila melanogaster
8 Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium

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