General Information of This Metabolic Reaction (MR) (ID: MR004487)
Formula
SVG example
Demethylation
Reactant 3-(3'-Hydroxy-4'-methoxyphenyl)propionic acid Product 3-(3',4'-Dihydroxyphenyl)propionic acid
Reactant Info Product Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004486 3-(3'-Hydroxy-4'-methoxyphenyl)-2-propionic acid 3-(3'-Hydroxy-4'-methoxyphenyl)propionic acid Unclear VS-12343 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004503 3-(3'-Hydroxy-4'-methoxyphenyl)propionic acid 3'-Hydroxy-4'-methoxyphenylacetic acid Reduction - Dehydroxylation VS-12343 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003504 DOPA 3,4-dihydroxyphenylpropionic acid(DPPA) Unclear L-phenylalanine [2]
MR004312 3-(4'-hydroxyphenyl)propionic acid 3-(3',4'-dihydroxyphenyl)propionic acid Oxidation - Hydrolyzationn Naringin [3]
MR004406 3-(4-Hydroxyphenyl)propanoic acid 3-(3,4-Dihydroxyphenyl)propanoic acid Oxidation - Hydrolyzationn N-nonylphenol [4]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003505 3,4-dihydroxyphenylpropionic acid(DPPA) DOPL Unclear L-phenylalanine [2]
MR004488 3-(3',4'-Dihydroxyphenyl)propionic acid 3'-4'-Dihydroxyphenylacetic acid Unclear VS-12343 [1]
MR004496 3-(3',4'-Dihydroxyphenyl)propionic acid 3-(3'-Hydroxyphenyl)propionic acid Reduction - Dehydroxylation VS-12343 [1]
MR004500 3-(3',4'-Dihydroxyphenyl)propionic acid 3-(4'-Hydroxyphenyl)propionic acid Unclear VS-12343 [1]
References
1 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium
2 Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine Res Microbiol. 2007 Jul-Aug;158(6):506-11. doi: 10.1016/j.resmic.2007.04.008.
3 Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity
4 4-n-nonylphenol degradation by the genus Metarhizium with cytochrome P450 involvement

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