Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003504)
Formula
SVG example
Reactant DOPA Product 3,4-dihydroxyphenylpropionic acid(DPPA)
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009123 ABBV-951 Levodopa Unclear - Unclear ABBV-951 [1]
MR005862 L-tyrosine DOPA Oxidation - Hydrolyzationn L-tyrosine [2]
MR003503 L-Tyrosine DOPA Unclear L-phenylalanine [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003508 DOPA DOPP Unclear L-phenylalanine [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004487 3-(3'-Hydroxy-4'-methoxyphenyl)propionic acid 3-(3',4'-Dihydroxyphenyl)propionic acid Oxidation - Demethylation VS-12343 [4]
MR004312 3-(4'-hydroxyphenyl)propionic acid 3-(3',4'-dihydroxyphenyl)propionic acid Oxidation - Hydrolyzationn Naringin [5]
MR004406 3-(4-Hydroxyphenyl)propanoic acid 3-(3,4-Dihydroxyphenyl)propanoic acid Oxidation - Hydrolyzationn N-nonylphenol [6]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003505 3,4-dihydroxyphenylpropionic acid(DPPA) DOPL Unclear L-phenylalanine [3]
MR004488 3-(3',4'-Dihydroxyphenyl)propionic acid 3'-4'-Dihydroxyphenylacetic acid Unclear VS-12343 [4]
MR004496 3-(3',4'-Dihydroxyphenyl)propionic acid 3-(3'-Hydroxyphenyl)propionic acid Reduction - Dehydroxylation VS-12343 [4]
MR004500 3-(3',4'-Dihydroxyphenyl)propionic acid 3-(4'-Hydroxyphenyl)propionic acid Unclear VS-12343 [4]
References
1 Scalable Asymmetric Syntheses of Foslevodopa and Foscarbidopa Drug Substances for the Treatment of Parkinson's Disease
2 Potent inhibitory effects of tyrosine metabolites on dihydropteridine reductase from human and sheep liver
3 Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine Res Microbiol. 2007 Jul-Aug;158(6):506-11. doi: 10.1016/j.resmic.2007.04.008.
4 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium
5 Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity
6 4-n-nonylphenol degradation by the genus Metarhizium with cytochrome P450 involvement

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