Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004658)
Formula
	Reactant	4-Hydroxyifosfamide	Product	4-Ketoifosfamide
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR004650	Ifosfamide	4-Hydroxyifosfamide	Oxidation - 4-hydroxylation	Ifosfamide	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR004659	4-Hydroxyifosfamide	4-Thioifosfamide	Conjugation - Glutathione conjugation	Ifosfamide	[2]
MR004651	4-Hydroxyifosfamide	Aldoifosfamide	Unclear	Ifosfamide	[2]

References
1	The KEGG resource for deciphering the genome
2	Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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