Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004659)
Formula Reactant 4-Hydroxyifosfamide Product 4-Thioifosfamide
Reactant Info Product Info
Metabolic Type Conjugation - Glutathione conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004650 Ifosfamide 4-Hydroxyifosfamide Oxidation - 4-hydroxylation Ifosfamide [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004658 4-Hydroxyifosfamide 4-Ketoifosfamide Unclear Ifosfamide [1]
MR004651 4-Hydroxyifosfamide Aldoifosfamide Unclear Ifosfamide [2]
References
1 The KEGG resource for deciphering the genome
2 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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