Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR004666)
Formula	CYP3A4 O-demethylation
	Reactant	Iloperidone		Product	Iloperidone P89
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)					DME Info
Metabolic Type	Oxidation - O-demethylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR004664	Iloperidone	Iloperidone P88	Reduction - Carbonyl reduction	Iloperidone	[1]
MR004665	Iloperidone	Iloperidone P95	Oxidation - Hydrolyzationn	Iloperidone	[1]

References
1	Iloperidone: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability, regulatory affairs, and an opinion. Expert Opin Drug Metab Toxicol. 2010 Dec;6(12):1551-64.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.