Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004787)
Formula
CYP1A2 ...
SVG example
8-hydroxylation
Reactant Mirtazapine Product 8-hydroxymirtazapine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - 8-hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004788 Mirtazapine Dimetilmirtazapine (DMR) Unclear Mirtazapine [1]
MR004785 Mirtazapine Mirtazapine-N-oxide Oxidation - N-oxidation Mirtazapine [2]
MR004786 Mirtazapine N-desmethylmirtazapine Oxidation - N-demethylation Mirtazapine [3]
References
1 Pharmacokinetics of mirtazapine and its main metabolites in Beagle dogs: a pilot study
2 FDA label:Mirtazapine
3 Clinical pharmacokinetics of mirtazapine

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