Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005116)
Formula
CYP2D6 ...
SVG example
O-demethylation
Reactant 6-beta-hydrocodol Product 6-beta-hydromorphol
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Oxidation - O-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005115 Hydrocodone bitartrate 6-beta-hydrocodol Reduction - 6-ketoreduction Hydrocodone bitartrate [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005121 6-beta-hydrocodol 6-beta-hydrocodol glucuronide conjugate Conjugation - O-glucuronidation Hydrocodone bitartrate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005111 Hydromorphone 6-beta-hydromorphol Reduction - 6-ketoreduction Hydrocodone bitartrate [1]
MR005113 6-beta-hydromorphol 6-beta-hydromorphol Conjugation - O-glucuronidation Hydrocodone bitartrate [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005112 6-beta-hydromorphol 6-beta-hydromorphol glucuronide conjugate 1 Conjugation - O-glucuronidation Hydrocodone bitartrate [1]
MR005113 6-beta-hydromorphol 6-beta-hydromorphol Conjugation - O-glucuronidation Hydrocodone bitartrate [1]
MR005117 6-beta-hydromorphol 6-beta-hydromorphol glucuronide conjugate 2 Conjugation - O-glucuronidation Hydrocodone bitartrate [1]
References
1 DrugBank(Pharmacology-Metabolism):Hydrocodone bitartrate

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