Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005174)
Formula
SVG example
Reactant Pirprofen Product Pyrrole M1
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005176 Pirprofen Amino-metabolite Unclear Pirprofen [1]
MR005169 Pirprofen Epoxide metabolite Unclear Pirprofen [1]
MR005172 Pirprofen Pirprofen glucuronide Conjugation - Glucuronidation Pirprofen [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005175 Pyrrole M1 Pyrrole metabolite glucuronide Conjugation - Glucuronidation Pirprofen [1]
References
1 High-performance liquid chromatographic determination of pirprofen and five of its metabolites in human plasma without hydrolysis and in human urine before and after chemical hydrolysis
2 Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes. Drug Metab Dispos. 1990 Sep-Oct;18(5):692-7.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.