Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005244)
Formula
SVG example
Reactant Roxithromycin Product Descladinose roxithromycin
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005245 Roxithromycin N-di-demethyl roxithromycin Oxidation - N-demethylation Roxithromycin [1], [2]
MR005246 Roxithromycin N-mono roxithromycin Oxidation - N-demethylation Roxithromycin [1], [2]
MR005239 Roxithromycin Roxithromycin metabolite M2 Oxidation - O-dealkylation Roxithromycin [1], [2]
MR005242 Roxithromycin Roxithromycin metabolite M4 Oxidation - O-demethylation Roxithromycin [2]
References
1 Metabolism of roxithromycin in phenobarbital-treated rat liver microsomes
2 Identification of the metabolites of roxithromycin in humans

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