Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005260)
Formula
SVG example
Reactant Sertindole Product 3'-fluoro-4'-hydroxy-sertindole
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005253 Sertindole 4-hydroxy-serindole Oxidation - Hydrolyzationn Sertindole [1]
MR005249 Sertindole 5-hydroxy-serindole Oxidation - Hydrolyzationn Sertindole [1]
MR005259 Sertindole Norsertindole Oxidation - N-dealkylation Sertindole [1], [2]
References
1 Metabolism of sertindole: identification of the metabolites in the rat and dog, and species comparison of liver microsomal metabolism
2 Sertindole : a review of its use in schizophrenia

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