Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005253)
Formula
SVG example
Hydrolyzationn
Reactant Sertindole Product 4-hydroxy-serindole
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005260 Sertindole 3'-fluoro-4'-hydroxy-sertindole Unclear Sertindole [1]
MR005249 Sertindole 5-hydroxy-serindole Oxidation - Hydrolyzationn Sertindole [1]
MR005259 Sertindole Norsertindole Oxidation - N-dealkylation Sertindole [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005255 4-hydroxy-serindole 4-0x0-sertindole Oxidation - Oxidationn Sertindole [1]
MR005258 4-hydroxy-serindole 4.5 Dihydroxy-serfindo Oxidation - Hydrolyzationn Sertindole [1]
MR005254 4-hydroxy-serindole Dehydrosertindole Oxidation - Oxidationn Sertindole [1]
References
1 Metabolism of sertindole: identification of the metabolites in the rat and dog, and species comparison of liver microsomal metabolism
2 Sertindole : a review of its use in schizophrenia

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