Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005429)
Formula Reactant Avapritinib Product M690
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Conjugation - Hydroxy glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005430 Avapritinib M499 Oxidation - Oxidationn deamination Avapritinib [1]
MR005428 Avapritinib Unclear Unclear Avapritinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010829 Dezocine M690 Unclear - Unclear Dezocine [2]
References
1 FDA label:Avapritinib
2 Avapritinib: First Approval

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