Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005593)
Formula
FMO1 ...
SVG example
N-hydroxylation
Reactant Risdiplam Product Risdiplam M1 metabolite
Reactant Info Product Info
Metabolic Enzyme Dimethylaniline oxidase 1 (FMO1) DME Info
Dimethylaniline oxidase 3 (FMO3) DME Info
Cytochrome P450 1A1 (CYP1A1) DME Info
Cytochrome P450 2J2 (CYP2J2) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A7 (CYP3A7) DME Info
Metabolic Type Oxidation - N-hydroxylation
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009657 RG-7916 Risdiplam M1 metabolite Oxidation - N-hydroxylation RG-7916 [1]
References
1 Effect of mild or moderate hepatic impairment on the pharmacokinetics of risdiplam

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