General Information of This Metabolic Reaction (MR) (ID: MR005608)
Formula
SVG example
Oxidationn
Reactant Sodium phenylbutyrate Product Phenylacetic acid
Reactant Info Product Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005606 Sodium phenylbutyrate Phenylacetyl-CoA Oxidation - Oxidationn Sodium phenylbutyrate [1]
MR005596 Sodium phenylbutyrate Phenylbutyryl-CoA Unclear Sodium phenylbutyrate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007824 Ipratropium Phenylacetic acid Hydrolysis - Hydrolysis Ipratropium [2]
MR008132 Penicillin Phenylacetic acid Unclear - Unclear Penicillin [3]
MR008108 Penicillin G Sodium Phenyl acetic acid Hydrolysis - Hydrolysis Penicillin G Sodium [4]
MR002019 Phenelzine Phenylacetic acid Hydrolysis - Hydrolysis Phenelzine [5]
MR002015 Phenethylamine Phenylacetic acid Unclear Phenelzine [5]
MR009197 3-(phenyl)propanoic acid 3-(phenyl)acetic acid Oxidation - Oxidation 3,4-Dihydroxycinnamic Acid [6]
MR004490 3'-Hydroxyphenylacetic acid Phenylacetic acid Unclear VS-12343 [7]
MR004498 3-(phenyl)propionic acid Phenylacetic acid Unclear VS-12343 [7]
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Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009198 3-(phenyl)acetic acid Benzoic acid Oxidation - Oxidation 3,4-Dihydroxycinnamic Acid [6]
References
1 Evidence for involvement of medium chain acyl-CoA dehydrogenase in the metabolism of phenylbutyrate
2 Ipratropium bromide: drug metabolism and pharmacokinetics
3 Ligand-induced conformational change in penicillin acylase
4 A breakthrough in enzyme technology to fight penicillin resistance-industrial application of penicillin amidase
5 Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine: a review J Psychiatry Neurosci. 1992 Nov;17(5):206-14.
6 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
7 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium

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