Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005690)
Formula	Oxidationn N-dealkylation
	Reactant	Ziprasidone	Product	(6-chloro-2-oxo-2,3-dihydro-1H-indol-5-yl)acetic acid
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Oxidationn N-dealkylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005684	Ziprasidone	3-(piperazine-1-yl)-1,2-benzisothiazole	Oxidation - Oxidationn N-dealkylation	Ziprasidone	[1]
MR005694	Ziprasidone	6-chloro-5-(2-piperazin-1-yl-ethyl)-1,3-dihydro-indol-2-one	Other reaction - Deacylation	Ziprasidone	[1]
MR005695	Ziprasidone	Dihydro-ziprasidone-sulfone	Multi-steps Reaction - Hydration; oxidation	Ziprasidone	[1]
MR005692	Ziprasidone	S-Methyl-dihydro-ziprasidone	Multi-steps Reaction - Methylationn; reductive cleavage	Ziprasidone	[1]
MR005688	Ziprasidone	Ziprasidone Sulfoxide	Oxidation - Oxidationn	Ziprasidone	[1], [2]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005691	(6-chloro-2-oxo-2,3-dihydro-1H-indol-5-yl)acetic acid	(6-chloro-2-oxo-2,3-dihydro-1H-indol-5-yl)acetic acid glucuronide metabolite	Conjugation - Glucuronidation	Ziprasidone	[1]

References
1	Metabolism and excretion of a new antipsychotic drug, ziprasidone, in humans
2	[Limits of jaw orthopedic treatment]

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