Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005688)
Formula
SVG example
Oxidationn
Reactant Ziprasidone Product Ziprasidone Sulfoxide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005690 Ziprasidone (6-chloro-2-oxo-2,3-dihydro-1H-indol-5-yl)acetic acid Oxidation - Oxidationn N-dealkylation Ziprasidone [1]
MR005684 Ziprasidone 3-(piperazine-1-yl)-1,2-benzisothiazole Oxidation - Oxidationn N-dealkylation Ziprasidone [1]
MR005694 Ziprasidone 6-chloro-5-(2-piperazin-1-yl-ethyl)-1,3-dihydro-indol-2-one Other reaction - Deacylation Ziprasidone [1]
MR005695 Ziprasidone Dihydro-ziprasidone-sulfone Multi-steps Reaction - Hydration; oxidation Ziprasidone [1]
MR005692 Ziprasidone S-Methyl-dihydro-ziprasidone Multi-steps Reaction - Methylationn; reductive cleavage Ziprasidone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005689 Ziprasidone Sulfoxide Ziprasidone Sulfone Oxidation - Oxidationn Ziprasidone [1], [2]
References
1 Metabolism and excretion of a new antipsychotic drug, ziprasidone, in humans
2 [Limits of jaw orthopedic treatment]

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