Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005710)
Formula	CYP2D6 Demethylation
	Reactant	Dexchlorpheniramine maleate	Product	Didesmethyl-chlorpheniramine
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 2D6 (CYP2D6)				DME Info
Metabolic Type	Oxidation - Demethylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005711	Dexchlorpheniramine maleate	N-desmethyl-chlorpheniramine	Oxidation - Demethylation	Dexchlorpheniramine maleate	[1]

References
1	The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine. Br J Clin Pharmacol. 2002 May;53(5):519-25.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.