Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR005773)
Formula	CYP3A4 ... Hydrolyzationn
	Reactant	Dutasteride		Product	1,2-dihydrodutasteride
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)					DME Info
Metabolic Enzyme	Cytochrome P450 3A5 (CYP3A5)					DME Info
Metabolic Type	Oxidation - Hydrolyzationn

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005771	Dutasteride	4'-hydroxydutasteride	Oxidation - Hydrolyzationn	Dutasteride	[1]
MR005772	Dutasteride	6beta-hydroxydutasteride	Oxidation - Hydrolyzationn	Dutasteride	[1]

References
1	LC-MS/MS determination of dutasteride and its major metabolites in human plasma

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