Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005817)
Formula
SVG example
Reactant Bufotenine Product 5-hydroxyindoleacetic acid
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005816 Methoxybufotenin Bufotenine Oxidation - O-demethylation Methoxybufotenin [1]
MR003311 5-Methoxytryptamine Bufotenine Conjugation - Methylation Melatonin [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003313 Bufotenine N,N-Dimethyltryptamine Unclear Melatonin [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007991 Hydroxyamphetamine Hydrobromide 5-hydroxyindoleacetic acid Unclear - Unclear Hydroxyamphetamine Hydrobromide [3]
MR006371 Serotonin 5-HIAA Unclear Serotonin [4]
References
1 Psychedelic 5-methoxy-N,N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actions. Curr Drug Metab. 2010 Oct;11(8):659-66.
2 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
3 Inhibition of brain type A monoamine oxidase and 5-hydroxytryptamine uptake by two amphetamine metabolites, p-hydroxyamphetamine and p-hydroxynorephedrine
4 GPR35 promotes neutrophil recruitment in response to serotonin metabolite 5-HIAA

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