General Information of This Metabolic Reaction (MR) (ID: MR004398)
Formula
SVG example
Reactant (2E)-3-(4-Hydroxyphenyl)prop-2-enoic acid Product 2-(4-Hydroxyphenyl)acetic acid
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004310 Naringenin p-Coumaric acid Other reaction - Ring cleavage reaction Naringin [1]
MR005876 Liquiritin metabolite M9 Liquiritin metabolite M10 Oxidation - Dehydrogenation Liquiritin [2]
MR004397 3-(4-Hydroxyphenyl)propanoic acid (2E)-3-(4-Hydroxyphenyl)prop-2-enoic acid Unclear N-nonylphenol [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004311 p-Coumaric acid 3-(4'-hydroxyphenyl)propionic acid Reduction - Hydrogenation Naringin [1]
MR004314 p-Coumaric acid Caffeic acid Oxidation - Hydrolyzationn Naringin [1]
MR004315 p-Coumaric acid Cinnamic acid Reduction - Dehydroxylation Naringin [1]
MR004405 (2E)-3-(4-Hydroxyphenyl)prop-2-enoic acid (2E)-3-(3,4-Dihydroxyphenyl)prop-2-enoic acid Oxidation - Hydrolyzationn N-nonylphenol [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005864 L-tyrosine p-hydroxyphenylacetate Unclear L-tyrosine [4]
MR003838 3-(4-Hydroxyphenyl) propionic acid (4-Hydroxyphenyl) acetic acid Unclear BE-14348A [5]
MR002017 4- hydroxyphenelzine 4-hydroxyphenylacetic acid Hydrolysis - Hydrolysis Phenelzine [6]
MR002016 Phenylacetic acid 4-hydroxyphenylacetic acid Oxidation - 4-Hydroxylation Phenelzine [6]
MR013574 5-(3',4',5'-trihydroxyphenyl)valeric acid 4'-hydroxyphenylacetic acid Unclear Epigallocatechin gallate [7]
MR004501 3-(4'-Hydroxyphenyl)propionic acid 4'-Hydroxyphenylacetic acid Unclear VS-12343 [8]
MR004404 2-(4-Hydroxyphenyl)acetic acid 2-(4-Hydroxyphenyl)acetic acid Unclear N-nonylphenol [3]
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Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013575 4'-hydroxyphenylacetic acid 3',4'-dihydroxyphenylacetic acid Unclear Epigallocatechin gallate [7]
MR013582 4'-hydroxyphenylacetic acid 3-methoxy-4'-hydroxyphenlacetic acid Unclear Epigallocatechin gallate [7]
MR013576 4'-hydroxyphenylacetic acid 4'-hydroxybenzoic acid Unclear Epigallocatechin gallate [7]
MR004502 4'-Hydroxyphenylacetic acid 4-Hydroxybenzoic acid Unclear VS-12343 [8]
MR004403 2-(4-Hydroxyphenyl)acetic acid (3,4-Dihydroxyphenyl)acetic acid Oxidation - Hydrolyzationn N-nonylphenol [3]
MR004399 2-(4-Hydroxyphenyl)acetic acid 1-(4-hydroxyphenyl)ethanone Unclear N-nonylphenol [3]
MR004404 2-(4-Hydroxyphenyl)acetic acid 2-(4-Hydroxyphenyl)acetic acid Unclear N-nonylphenol [3]
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References
1 Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity
2 A comprehensive profiling and identification of liquiritin metabolites in rats using ultra-high-performance liquid chromatography coupled with linear ion trap-orbitrap mass spectrometer
3 4-n-nonylphenol degradation by the genus Metarhizium with cytochrome P450 involvement
4 Potent inhibitory effects of tyrosine metabolites on dihydropteridine reductase from human and sheep liver
5 High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
6 Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine: a review J Psychiatry Neurosci. 1992 Nov;17(5):206-14.
7 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate
8 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium

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