Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006132)
Formula
SVG example
O-demethylation
Reactant KB-2796 Product Lomerizine M5
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - O-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006131 KB-2796 1-[Bis(4-fluorophenyl)methyl]piperazine Oxidation - N-dealkylation KB-2796 [1]
MR006133 KB-2796 Lomerizine M3 Oxidation - Hydrolyzationn KB-2796 [1]
References
1 [Metabolism of lomerizine hydrochloride (KB-2796) in rats]

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