Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006155)
Formula
SVG example
Aromatic hydroxylation
Reactant AC-1802 Product p-Hydroxyphenylaprindine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Aromatic hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006156 AC-1802 Desethylaprindine Oxidation - N-dealkylation AC-1802 [1]
MR006154 AC-1802 N-[3-(N,NDiethylamino)propyl]-N-phenyl-2-aminoindan-5-ol Oxidation - Aromatic hydroxylation AC-1802 [1]
References
1 Cytochrome P450 inactivation by pharmaceuticals and phytochemicals: therapeutic relevance Drug Metab Rev. 2008;40(1):101-47. doi: 10.1080/03602530701836704.

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