Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006186)
Formula Reactant 3beta-sulfated-tibolone Product 3alpha-17beta-disulfated-tibolone
Reactant Info Product Info
Metabolic Enzyme Sulfotransferase 1E1 (SULT1E1) DME Info
Sulfotransferase 2B1 (SULT2B1) DME Info
Sulfotransferase 2A1 (SULT2A1) DME Info
Metabolic Type Conjugation - Sulfation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006184 3beta-OH-tibolone 3beta-sulfated-tibolone Conjugation - Sulfation Tibolone [1], [2], [3]
References
1 Sulfation of tibolone and tibolone metabolites by expressed human cytosolic sulfotransferases. J Steroid Biochem Mol Biol. 2004 Apr;88(4-5):383-91.
2 Sulfation of tibolone metabolites by human postmenopausal liver and small intestinal sulfotransferases (SULTs). Steroids. 2006 May;71(5):343-51.
3 Antioxidant effect of the active metabolites of tibolone

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