Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006193)
Formula
SVG example
Hydrolyzationn
Reactant Tienilic acid Product 5-Hydroxy-tienilic Acid
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006192 Tienilic acid Thiophene-4,5-epoxide Oxidation - Epoxidation Tienilic acid [1]
MR006190 Tienilic acid Ticrynafen S-oxide Oxidation - Oxidationn Tienilic acid [1]
MR006191 Tienilic acid Tienilic acid-s-oxide Oxidation - S-oxidation Tienilic acid [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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