Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006195)
Formula
SVG example
Reactant 4-demethyltranilast Product Tranilast metabolite N-3-S
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006194 Tranilast 4-demethyltranilast Oxidation - 4-demethylation Tranilast [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006196 4-demethyltranilast Tranilast metabolite N-3-G Conjugation - Glucuronidation Tranilast [1], [2]
References
1 Glucuronidation of antiallergic drug, Tranilast: identification of human UDP-glucuronosyltransferase isoforms and effect of its phase I metabolite. Drug Metab Dispos. 2007 Apr;35(4):583-9.
2 Simultaneous determination of tranilast and metabolites in plasma and urine using high-performance liquid chromatography

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