Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006196)
Formula Reactant 4-demethyltranilast Product Tranilast metabolite N-3-G
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006194 Tranilast 4-demethyltranilast Oxidation - 4-demethylation Tranilast [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006195 4-demethyltranilast Tranilast metabolite N-3-S Unclear Tranilast [1], [2]
References
1 Glucuronidation of antiallergic drug, Tranilast: identification of human UDP-glucuronosyltransferase isoforms and effect of its phase I metabolite. Drug Metab Dispos. 2007 Apr;35(4):583-9.
2 Simultaneous determination of tranilast and metabolites in plasma and urine using high-performance liquid chromatography

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