Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006494)
Formula
SVG example
C-dealkylation
Reactant Y-100032 Product Apli-da
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - C-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006497 Y-100032 Apli-dm Oxidation - C-dealkylation Y-100032 [1]
MR006496 Y-100032 Apli-h Oxidation - Hydrolyzationn Y-100032 [1]
MR006498 Y-100032 Unclear Unclear Y-100032 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006495 Apli-da Apli-da/h Oxidation - Hydrolyzationn Y-100032 [1]
References
1 In vitro characterization of the human biotransformation pathways of aplidine, a novel marine anti-cancer drug. Invest New Drugs. 2007 Feb;25(1):9-19.

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