Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006496)
Formula
SVG example
Hydrolyzationn
Reactant Y-100032 Product Apli-h
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006494 Y-100032 Apli-da Oxidation - C-dealkylation Y-100032 [1]
MR006497 Y-100032 Apli-dm Oxidation - C-dealkylation Y-100032 [1]
MR006498 Y-100032 Unclear Unclear Y-100032 [1]
References
1 In vitro characterization of the human biotransformation pathways of aplidine, a novel marine anti-cancer drug. Invest New Drugs. 2007 Feb;25(1):9-19.

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