Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006523)
Formula
SVG example
Oxidationn
Reactant Citalopram hydrobromide Product Citalopram-N-oxide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006522 Citalopram hydrobromide Citalopram propionaldehyde Oxidation - Oxidationn Citalopram hydrobromide [1]
MR006517 Citalopram hydrobromide Demethylcitalopram Oxidation - N-demethylation Citalopram hydrobromide [2], [1]
References
1 Analytical methodologies for the enantiodetermination of citalopram and its metabolites
2 PharmGKB summary: citalopram pharmacokinetics pathway. Pharmacogenet Genomics. 2011 Nov;21(11):769-72.

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