Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006517)
Formula
CYP2D6 ...
SVG example
N-demethylation
Reactant Citalopram hydrobromide Product Demethylcitalopram
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Oxidation - N-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006522 Citalopram hydrobromide Citalopram propionaldehyde Oxidation - Oxidationn Citalopram hydrobromide [1]
MR006523 Citalopram hydrobromide Citalopram-N-oxide Oxidation - Oxidationn Citalopram hydrobromide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006521 Demethylcitalopram Citalopram propionaldehyde Oxidation - Oxidationn Citalopram hydrobromide [1]
MR006518 Demethylcitalopram Didemethylcitalopram Oxidation - N-demethylation Citalopram hydrobromide [1]
References
1 Analytical methodologies for the enantiodetermination of citalopram and its metabolites

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