Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006524)
Formula
ADA
SVG example
Reactant Cladribine Product 2-chlorodeoxyinosine
Reactant Info Product Info
Metabolic Enzyme Adenosine aminohydrolase (ADA) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006526 Cladribine 2-chloro-2'-deoxyadenosine-5'-triphosphate Unclear Cladribine [1]
MR006527 Cladribine Glucuronide conjugates of 2-CdA Unclear Cladribine [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006525 2-chlorodeoxyinosine 2-Chlorohypoxanthine Unclear Cladribine [2]
References
1 Potential mechanisms of action related to the efficacy and safety of cladribine. Mult Scler Relat Disord. 2019 May;30:176-186.
2 Comparison of the in vitro and in vivo metabolism of Cladribine (Leustatin, Movectro) in animals and human

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